# Injection of high blood pressure #
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## Of hypertension gout ##
Una sa lahat, ang mga Beta-blocker ay karaniwang ibinibigay sa mga pasyente na may heart failure, aortic aneurysm, pagkatapos ng myocardial infarction, at sa mga kababaihan na nasa edad ng pagbubuntis, lalo na sa mga kababaihang nagpaplano ng pagbubuntis. Madalas matanggap ng katawan ang Beta-blocker, pero maaari rin itong magdulot ng pantal sa balat at bradycardia – sobrang bagal ng tibok ng puso. Of hypertension in gout: A dangerous Combination
High blood pressure and gout — two diseases that seem to be at first glance have little to each other. But a closer look shows that her health can affect work significantly, and the risk for further complications will increase significantly.
What is gout and high blood pressure are?
Gout is an inflammatory joint disease which is caused by an increased concentration of uric acid in the blood. When the body produces more uric acid than it can eliminate, to form crystals in the joints — usually in the Big toe. This leads to severe pain, swelling, and redness.
High blood pressure, medically called hypertension, is when blood pressure is consistently above the normal value of 120/80 mmHg. In the long term, it damages blood vessels and organs such as the heart, kidneys and brain and increases the risk of heart attack and stroke.
The common risk factors
Both diseases share a number of risk factors:
Obesity: A higher percentage of body fat promotes both the formation of uric acid, as well as the blood pressure.
Nutrition: high intake of meat, alcohol (especially beer) and sugar-containing beverages increases the level of uric acid and can increase blood pressure.
Lifestyle: lack of exercise and Stress contribute to the development of both diseases.
Genetics: A family history can increase the risk.
How do gout and hypertension each other?
Studies show that patients with gout have a significantly higher risk for high blood pressure. The cause probably lies in the inflammatory reaction that occurs in gout: inflammation can damage the blood vessels and the Regulation of blood pressure and disturb.
Conversely, high blood pressure can affect renal function. Since the kidneys are the elimination of uric acid in charge, leads to renal performance to an increase in the concentration of uric acid and seizures, thus, a higher risk for Gout.
Treatment and prevention: An integrated approach
The treatment should take into account both disorders at the same time:
Drug Therapy:
Gout medications can be used, the uric acid production to reduce or promote the excretion (e.g., Allopurinol).
Hypertension is treated with antihypertensive drugs, with some substances (such as ACE‑inhibitors) in addition, the uric acid excretion can support.
Diet:
Reduction of purinreichen foods (red meats, offal).
Waiver of alcohol, or at least a significant limitation.
More fruit, vegetables and complex carbohydrates.
Adequate fluid intake (at least 2 liters of water per day), uric acid excrete.
Movement:
Regular, gentle exercise (walking, Swimming) lowers blood pressure and stimulates the metabolism.
Weight loss:
A healthy body weight relieves the joints and at the same time lowers the blood pressure.
Regular Controls:
Monitoring of uric acid levels and blood pressure by a doctor.
Conclusion
Gout and high blood pressure to form a dangerous Duo, this can result in untreated development to significant damage to Health. Through an integrated approach in the diagnosis and therapy — including lifestyle changes and targeted medication, however, can relieve symptoms, and to further minimize risks. Early education and active prevention are, therefore, of crucial importance for the quality of life of those Affected.
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Injection therapy in arterial hypertension: indications and practice
Arterial hypertension, also called high blood pressure is known, is one of the most common cardiovascular disease and often requires a long-term drug therapy. In certain clinical situations, however, it can be a fast and effective blood pressure reduction by means of injection is necessary.
Indications for injectable therapy
Parenteral (injectable) blood pressure therapy is typically used in the following conditions:
Hypertensive emergencies (e.g., hypertensive encephalopathy, acute coronary syndromes, disseknierende aortic aneurysms), in which a rapid drop in blood pressure life-saving it can be.
Inability to oral medication (for example, in the case of severe Nausea, vomiting, loss of consciousness).
Postoperative blood pressure regulation, particularly after cardiac surgery.
Severe pre-eclampsia or eclampsia in pregnant women in whom rapid control of blood pressure is necessary.
Common injectable substances
Among the most commonly used injectable antihypertensive agents:
Nitroglycerin (nitro Glycerinum): A vasodilator that increases the venous vascular capacity, and so the heart preload, lowers. It is often used in acute heart failure, and hypertensive emergencies with coronary ischemia.
Nicardipine (Nicardipinum): A calcium channel blocker of the dihydropyridine class, which has a strong vasodilating effect, and peripheral vascular resistance decreases.
Enalaprilat (Enalaprilatum): The injectable ACE inhibitor that blocks the Renin‑Angiotensin‑aldosterone‑System (RAAS) and leads to a decrease in the peripheral vascular resistance.
Labetalol (Labetalolum): A α‑ and β‑adrenergic receptors blocker with rapid onset of action, will find in hypertensive crisis situations, including pre-eclampsia, application.
Urapidil (Urapidilum): A peripherally-acting α1‑adrenergic blocker with additional Central 5‑HT1A‑agonist effect, which allows a controlled reduction in blood pressure.
Application procedures
The injection can be carried out in various forms:
A Bolus injection: A single injection to the blood pressure-correction (e.g., 25 mg of Labetalol I. V.).
Infusion: Continuous administration over a period of time to maintain a stable blood pressure (e.g., Nitroglycerin Infusion with titratable Rate).
Titration: a gradual increase or decrease in the dose under the constant blood pressure monitoring to avoid Over‑ or under-dosage.
Monitoring and side-effects
While injection therapy is a continuous Monitoring of the vital parameters (blood pressure, heart rate, oxygen saturation) are required. Possible side effects include:
Hypotension
Bradycardia or tachycardia
Headache (particularly nitrates)
Flushes
Shortness of breath (in the case of Overdose or faster injection)
Conclusion
The injection of blood-pressure-lowering medication is a major therapeutic tool in the treatment of hypertensive emergencies and situations where oral therapy is not possible. The choice of the drug and the mode of Application, need to be individually according to the clinical picture and the Comorbidities of the patient. Careful Monitoring during therapy is essential to ensure the effectiveness, and to detect adverse effects at an early stage.
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## The first aid in case of cardiovascular diseases ##
The first aid in case of cardiovascular diseases: a life saved by fast Acting
Cardiovascular disease causes are one of the leading death in the world. Often minutes or even seconds to decide about life and death. Therefore, it is important that everyone knows the basics of First aid in case of such emergencies.
What are the signs speak for a cardiac emergency?
A heart attack or other critical cardiovascular disorder often shows by any of the following symptoms:
violent, oppressive middle, which may radiate to the Arm, the back, neck, or jaw chest pain;
Shortness of breath or feeling of tightness in the chest;
profuse sweating, pallor, or Nausea;
sudden weakness, dizziness, or unconsciousness.
In the case of suspicion of a cardiac emergency, quick and correct measures are crucial.
Step-by-step: how to correctly helps
Keep calm and call for help. Immediately to the emergency (in Germany: 112) to choose. Clear and precise information: location, condition of the Affected, symptoms.
Consciousness and breathing check. The Concerned respond, gently shaking, and his reaction are looking for. Breathing watch (movement of the chest, the air flow on the cheek).
Location stabilize. The Affected person is unconscious but breathing, the recovery position. He is unconscious and is not breathing normally, immediately begin resuscitation.
Cardio‑pulmonary resuscitation to start.
The victim on his back on a firm surface bearings.
Both hands on top of each other in the middle of the chest.
With the body weight of 30 depth of Chest compressions (depth: about 5-6 cm, speed: 100-120 per Minute) to perform.
Then, 2 artificial breaths (if trained and ready).
This process will continue until the emergency services arrive or a Defibrillator is available.
Defibrillation use. An automated external Defibrillator (AED) is available, immediately. The devices provide audible instructions — easy to follow instructions. Every Minute of delay reduces the chances of Survival by about 10%.
The affected support. The Patient is aware of him in a quiet location and fresh air will provide. In the case of breast pain — if available and prescribed a dose of Nitroglycerin may be administered (by a doctor).
Why is training so important?
Many people hesitate in emergency situations because they are afraid of doing something wrong. However, even a perfectly executed revival is better than none at all. In Germany, the laity may help without any legal consequences for the so — called No‑Harm principle protects you.
Regular First aid courses provide safety and to be familiar with the correct procedures. Associations such as the German Red cross or Johanniter‑unfall‑Hilfe offer such courses.
Conclusion
The First aid in case of cardiovascular diseases can save lives. Quick symptoms, quiet Action and the right action — in particular, the early heart‑lung Detect resuscitation and Defibrillation increase the chances of Survival significantly. Anyone can learn how to help. And everyone can save a life.
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